Manufacture of interferon
US3951740A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 7, 1975 |
| Grant date | Apr 20, 1976 |
| Priority date | — |
| Expiry date | Jan 7, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/555
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to the production of interferon. In accordance with the present invention, interferon is produced by growing a continuous cell line in a suspension culture, the cells first being primed by cultivation in the presence of interferon specific to the cells and L-glutamine, interferon production being initiated by contacting the cells with a high concentrated suspension of virus inducer, then removing the virus and incubating the cells in a nutrient medium. Concentration and purification to give interferon preparations can be effected by known methods. Various types of interferon preparations of high titre have been produced on an industrial scale.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.