Penicillins substituted with heterocyclic groups
US3951955A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 25, 1974 |
| Grant date | Apr 20, 1976 |
| Priority date | — |
| Expiry date | Jul 25, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D499/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A penicillin of the formula: ##SPC1## Wherein A is a substituted or unsubstituted condensed aromatic carbocyclic or heterocyclic ring, R is hydrogen or lower alkyl, X is oxygen or sulfur, Y is hydrogen, lower alkyl, lower alkanoyl or lower alkoxycarbonyl and Z is phenyl or thienyl which can be produced by reacting 6-aminopenicillanic acid or its ester with a carboxylic acid of the formula: ##SPC2## Wherein A, R, X, Y and Z are each as defined above or its reactive derivative. The said penicillin and its non-toxic salts have a broad antimicrobial spectrum against various gram-positive and gram-negative bacteria, and they exhibit characteristically a strong antimicrobial activity against Pseudomonas.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.