Patent · US Expired

Phenoxypropanolpiperazines

US3951983A · kind A · utility

9Cited by
3References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 2, 1974
Grant dateApr 20, 1976
Priority date
Expiry dateAug 2, 1994

Classification

  • Technology area (CPC H)Electricity
  • CPC primaryH04N5/9207
  • WIPO fieldAudio-visual technology
  • WIPO sectorElectrical engineering

Abstract

A series of novel substituted phenoxypropyl piperazine derivatives have been prepared by reacting the appropriate 1-phenoxy-2,3-epoxypropane compound with 1-phenoxy-3-(4-phenylpiperazine-1-yl)propan-2-ols suitable N-phenylpiperazine reagent. The resulting 1-phenoxy13-(4-phenylpiperazine-1-yl)propan-2-ols are useful in the field of chemotherapy as antihypertensive agents. Preferred members include compounds having an acetamidomethyl, carboxymethyl or carbamoylmethyl group substituted on the phenyl ring of the phenoxy moiety. Alternate methods of preparation are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.