Controlled release delivery system by an osmotic bursting mechanism
US3952741A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 9, 1975 |
| Grant date | Apr 27, 1976 |
| Priority date | — |
| Expiry date | Jan 9, 1995 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB65D65/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An osmotic dispenser comprised of (1) a water permeable membrane forming part or all of the walls of an enclosure surrounding (2) an active agent, and in some cases (3) an additional compound known as an osmotic attractant which together exhibits an osmotic pressure against water. When placed in an aqueous environment water is osmotically drawn into the enclosure by the combined action of the agents (2) and (3) which distends and swells the enclosure until the membrane or some other part of the enclosure wall reaches the point of ultimate elongation and a portion of the wall yields and ruptures releasing the contents of the enclosure to the environment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.