Patent · US Expired

Naphthyridine-3-carboxamido-benzylpenicillins and salts thereof

US3954733A · kind A · utility

20Cited by
3References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 13, 1973
Grant dateMay 4, 1976
Priority date
Expiry dateDec 13, 1993

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D499/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel penicillins of the formula: ##SPC1## Wherein the ring A is a benzene ring or a 5 or 6-membered heteroaromatic ring containing one or two nitrogen atoms as the hetero atom, on which one or more of lower alkyl, lower alkoxy, lower alkylthio, lower haloalkyl, lower alkylenedioxy, halogen, hydroxyl, nitro, free or protected amino, lower alkylamino, di(lower)alkylamino and lower alkanoylamino may be present, Z is a nitrogen atom or a methylene group, X is an oxygen atom or a sulfur atom, Y is a hydrogen atom, a lower alkoxycarbonyl group or a lower alkanoyl group, R.sub.1 is a free or protected hydroxyl group and R.sub.2 and R.sub.3 are each a hydrogen atom or a halogen atom, and their non-toxic pharmaceutically acceptable salts, and their preparation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.