Heterocyclic aluminum compounds and process for their preparation
US3956352A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 28, 1973 |
| Grant date | May 11, 1976 |
| Priority date | — |
| Expiry date | Dec 28, 1993 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q15/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A heterocyclic aluminum compound of the formula ##EQU1## wherein n is 1 or 2. When n is 1, Z is --CH=CH--. When n is 2, Z is either --(CH.sub.2).sub.m wherein m is 0-6, or a heteroatom selected from --O--, --S--, >SO, >SO.sub.2 or >N--COR' where R' is an aliphatic hydrocarbon of 1-17 carbon atoms, --(CH.sub.2).sub.q --C.sub.6 H.sub.5 where q is 0 or 1, styryl, diphenyl methyl or phenyl optionally substituted by chlorine, fluorine, methyl and alkoxy having 1-4 carbon atoms. The compound can be prepared by reacting isopropyl aluminate with an .omega.-diol of the formula ##EQU2## wherein Z has the meaning given above and then reacting the resulting product with dry HCl or an acyl chloride of the formula R'--COCl wherein R' has the meaning given above. The heterocyclic aluminum compound exhibits antiperspirant activity. It can be used in cosmetic antiperspirant compositions comprising a cosmetic vehicle and about 0.2-30 weight percent thereof based on the weight of said composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.