Substituted nitrobenzophenone derivatives
US3957777A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 3, 1974 |
| Grant date | May 18, 1976 |
| Priority date | — |
| Expiry date | Jul 3, 1994 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New compounds of the formula (I), ##SPC1## wherein PA1 R.sub.1 and R.sub.2 each stand for a saturated or unsaturated, straightchained or branched alkyl group, an aralkyl group, a saturated or unsaturated cycloalkyl group or an aryl group, or PA1 R.sub.1 and R.sub.2 together with the adjacent nitrogen atom form a substituted or unsubstituted heterocyclic group which can contain a further oxygen or nitrogen hetero atom, But when R.sub.1 is methyl, R.sub.2 is a group other than methyl, are prepared by reacting a compound of the formula (II), ##SPC2## wherein X stands for halogen, with a secondary amine of the general formula (III), EQU r.sub.1 --nh--r.sub.2. (iii) the new compounds of the general formula (I), as well as their pharmaceutical acceptable acid addition salts or quaternary ammonium salts are active primarily in the induction of liver microsomal enzyme, but they also possess antipyretic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.