Antiviral compositions containing bis-basic ketones of thioxanthene
US3957988A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 20, 1973 |
| Grant date | May 18, 1976 |
| Priority date | — |
| Expiry date | Feb 20, 1993 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D335/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The novel bis-basic ketones of thioxanthene have antiviral activity when administered orally and parenterally. These compounds are represented by the following formula: ##SPC1## Wherein A is a straight or branched alkylene chain having from 1 to about 6 carbon atoms; and each Y is PA1 A. the group ##EQU1## wherein R.sup.1 and R.sup.2 are individually hydrogen or lower alkyl having from 1 to about 4 carbon atoms; or PA1 B. the group ##EQU2## WHEREIN N IS A WHOLE INTEGER OF 4 OR 5, AND R.sup.3 is hydrogen or lower alkyl having from 1 to about 4 carbon atoms and can be linked to any one of the carbon atoms of the heterocyclic group; or PA1 C. the group ##EQU3## wherein X is oxygen or NR.sup.4, and R.sup.4 is hydrogen or lower alkyl of from 1 to about 4 carbon atoms; or pharmaceutically acceptable acid addition salts of said base. These new compounds can be prepared by several different methods which are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.