Aminoalkyl esters of 2-anilino-nicotinic acids
US3959272A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 4, 1973 |
| Grant date | May 25, 1976 |
| Priority date | — |
| Expiry date | Jun 4, 1993 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/80
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Amino alkyl 2-anilino nicotinates of the formula: ##SPC1## In which A is CH.sub.2 CH.sub.2 or CH.sub.2 C(CH.sub.3).sub.2, R.sub.1 and R.sub.2 are both methyl or together with the adjacent nitrogen make up a piperidino, morpholino or N-methylpiperazino ring, and R.sub.3 and R.sub.4 are both hydrogen or are both methyl in positions 2 and 3 or 2 and 6 of the phenyl nucleus or R.sub.3 is chlorine in position 2, 3 or 5 and R.sub.4 is methyl in position 2, 4 or 6 of the phenyl nucleus and their acid addition salts, made by reaction of the corresponding amino alkyl chloride with an alkali metal salt of the appropriate 2-anilino nicotinic acid, have interesting analgesic, anti-inflammatory, and psychotropic properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.