Derivatives of 4,6 dioxopyrido[3,2-g]quinoline 2,8 dicarboxylic acid
US3959289A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 11, 1974 |
| Grant date | May 25, 1976 |
| Priority date | — |
| Expiry date | Dec 11, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C205/37
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel chemical compounds of the formula: ##SPC1## Wherein PA1 R is selected from the group consisting of hydrogen, alkyl from one to three carbon atoms, inclusive, phenyl, alkali metal, or an amine cation; PA1 X and Y can be the same or different and are selected from the group consisting of hydrogen, alkyl of from one to six carbon atoms, inclusive, cycloalkyl of 5 or 6 carbon atoms, inclusive, phenyl, hydroxyl, alkoxy having from one to three carbon atoms, inclusive, halogen, trifluoromethyl, cyano, carboxyamide and O C-OQ, ##EQU1## where Q is selected from the group consisting of hydrogen, alkyl from one to three carbon atoms, inclusive, alkali metal, and an amine cation, with the proviso that where PA1 R is hydrogen, alkali metal or an amine cation, then Q is the same as R, and where PA1 R is phenyl or alkyl from one to three carbon atoms, then Q is phenyl or alkyl from one to three carbon atoms; and PA1 Z is selected from the group consisting of hydrogen, alkyl from one to three carbon atoms, inclusive, and phenyl. The compounds are formulated with pharmaceutical carriers for oral or parenteral administration, with insufflation being the preferred method. The compositions are …
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