Labeling of indocyanine green with carrier-free iodine-123

US3959455A · kind A · utility

Assignee

• The United States of America as represented by the United States Energy Research and Development Administration · US

Inventors

• Azizullah N. Ansari · Mount Sinai, US
• Richard M. Lambrecht · West Allis, US
• Carol S. Redvanly · Upton, US
• Alfred P. Wolf · Setauket, US

Key dates

• Filing date: Jul 1, 1975
• Grant date: May 25, 1976
• Expiry date: Jul 1, 1995

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2123/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The method of labeling indocyanine green (ICG) with carrier-free iodine-123 comprising the steps of condensing xenon-123 on crystals of ICG followed by permitting decay of the .sup.123 Xe a sufficient length of time to produce .sup.123 I-electronically excited ions and atoms which subsequently label ICG.