Polyalkylene glycols used for the preparation of peptides

US3960830A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Ernst Bayer
• Manfred Mutter · Crissier, CH

Key dates

• Filing date: Dec 4, 1974
• Grant date: Jun 1, 1976
• Expiry date: Dec 4, 1994

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K1/042
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A process for the synthesis of peptides in a liquid phase wherein the peptide product, and intermediates in the peptide synthesis, are bound to a polyalkylene glycol polymer and wherein the polymer-bound peptide is separated from the liquid phase, e.g. for purposes of isolation or purification, by crystallizing the polymer-bound peptide.