Patent · US Expired

2-Aminomethyl benzimidazole derivatives

US3962256A · kind A · utility

1Cited by

1References

7Claims

0Family size

Assignee

Delalande S.A. · FR

Inventors

Claude P. Fauran · Paris, FR
Jeannine A. Eberle · Chatou, FR
Guy M. Raynaud · Paris, FR
Nicole A. M. Dorme · Paris, FR

Key dates

Filing date	Jun 20, 1974
Grant date	Jun 8, 1976
Priority date	—
Expiry date	Jun 20, 1994

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D235/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Compounds having the formula ##EQU1## WHEREIN Ar is phenyl optionally substituted by one or more halogens, alkyl having 1 to 4 carbons or alkoxy containing up to 4 carbons, and R.sub.1 and R.sub.2 each is alkyl having one to 4 carbons or ##EQU2## is piperidino, pyrrolidino, morpholino and hexamethyleneimino. The compounds are prepared by reacting the corresponding 2-chloromethyl benzimidazole with ##EQU3## The compounds possess analgesic, antihypertensive, gastric antisecretory, antiinflammatory, antibronchoconstrictive, anticholinergic, spasmolytic, sedative, antiulcerous, vasodilatatory, central nervous system stimulant, antiarythmic, diuretic and antihistaminic properties.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.