Patent · US Expired

9,11,15-Trihydroxy prost-5-enoic acid analogues

US3962312A · kind A · utility

26Cited by
1References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 19, 1973
Grant dateJun 8, 1976
Priority date
Expiry dateSep 19, 1993

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D309/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Prostaglandin compounds of the formula: ##SPC1## Wherein A represents a grouping of formula II, III or IV indicated below and (i)R.sub.1 represents an unsubstituted n-butyl, n-pentyl, n-hexyl or n-heptyl radical, or such a radical carrying one, two or three alkyl substituents of 1 to 4 carbon atoms, or R.sub.1 represents a methyl, ethyl, propyl or butyl radical carrying a phenyl, cyclohexyl or cyclopentyl substituent, R.sub.2 represents a hydrogen atom or an alkyl radical of 1 to 4 carbon atoms, and R.sub.3 represents a hydrogen atom, or (ii) R.sub.1 represents n-butyl, or n-butyl or n-pentyl carrying one, two or three alkyl substituents of 1 to 4 carbon atoms, or R.sub.1 represents a methyl, ethyl, propyl or butyl radical carrying a phenyl, cyclohexyl or cyclopentyl substituent, R.sub.2 represents a hydrogen atom or an alkyl radical of 1 to 4 carbon atoms, and R.sub.3 represents an alkyl radical of 1 to 4 carbon atoms are disclosed. These compounds exhibit characteristic prostaglandin-like activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.