Adamantyl thioamides
US3962328A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 28, 1975 |
| Grant date | Jun 8, 1976 |
| Priority date | — |
| Expiry date | Apr 28, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Adamantyl thioamides having the formula: ##EQU1## in which Ad is adamantyl or alkyl-substituted adamantyl; m is a number of 0 or 1, n is a number of 1 or 2, with the proviso that m is 1, when n is 2; and the aminothiocarbonylmethyl or the aminothiocarbonyl group is bonded to a bridgehead carbon atom of the adamantane ring, are prepared by reacting a nitrile having the formula EQU Ad[(CH.sub.2).sub.m CN].sub.n (II) in which Ad, m and n have the same meaning as above, with hydrogen sulfide in the presence of a catalyst. The compounds possess antiviral activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.