Patent · US Expired

Adamantyl thioamides

US3962328A · kind A · utility

1Cited by
9References
1Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 28, 1975
Grant dateJun 8, 1976
Priority date
Expiry dateApr 28, 1995

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2603/74
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Adamantyl thioamides having the formula: ##EQU1## in which Ad is adamantyl or alkyl-substituted adamantyl; m is a number of 0 or 1, n is a number of 1 or 2, with the proviso that m is 1, when n is 2; and the aminothiocarbonylmethyl or the aminothiocarbonyl group is bonded to a bridgehead carbon atom of the adamantane ring, are prepared by reacting a nitrile having the formula EQU Ad[(CH.sub.2).sub.m CN].sub.n (II) in which Ad, m and n have the same meaning as above, with hydrogen sulfide in the presence of a catalyst. The compounds possess antiviral activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.