8-Alkyl and alkenyl-10-hydroxy-5H[1]benzopyranopyridine derivatives having polyphagic activity
US3962448A · kind A · utility
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Key dates
| Filing date | Apr 21, 1975 |
| Grant date | Jun 8, 1976 |
| Priority date | — |
| Expiry date | Apr 21, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
8-Alkyl and alkenyl-10-hydroxy-5H[1]benzopyranopyridines are prepared by dehydrogenation of the corresponding N-benzyl or N-hydrogen-8-alkyl or alkenyl-1,2,3,4-tetrahydro-5H[1]benzopyranopyridines in a high boiling solvent in the presence of a noble metal dehydrogenation catalyst. Alkyl derivatives of 5-11 carbon atoms are particularly useful. Also the O-acetyl derivatives are very useful. The compounds are central nervous system depressants and animal polyphagic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.