Tetracyclic imidazo [2,1-b] quinazolinone derivatives
US3963720A · kind A · utility
6Cited by
1References
18Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 21, 1974 |
| Grant date | Jun 15, 1976 |
| Priority date | — |
| Expiry date | Jun 21, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are compounds which are tetracyclic derivatives of imidazo[2,1-b]quinazolinones, e.g., 6-(p-fluorobenzyl)-1,2,3,4,4a,12a-hexahydrobenzimidazo[2,1-b]quinazolin-11 (6H)-one. The compounds are also useful as bronchodilator agents, and certain compounds are also useful as tranquillizers and sedative/hypnotic agents. The compounds may be prepared by reacting an isatoic anhydride with a 2-organomercapto-hexahydrobenzimidazole or hexahydrocyclopentimidazole such as 3a,4,5,6,7,7a-hexahydro-2-mercaptomethyl-3H-benzimidazole.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.