1-(Substituted-aminoalkyl)-3-benzoyl-4-hydroxy-4-phenylpiperidines and related compounds
US3965104A · kind A · utility
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7Claims
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Key dates
| Filing date | Jun 16, 1975 |
| Grant date | Jun 22, 1976 |
| Priority date | — |
| Expiry date | Jun 16, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/52
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
1-(Substituted-aminoalkyl)-3-benzoyl-4-hydroxy-4-phenylpiperidines and related compounds having anti-arrhythmic activity are described herein. The 3-benzoyl compounds can be prepared by condensing the appropriate diamine with acetophenone and formaldehyde. The related 3-(.alpha.-hydroxybenzyl) compounds are prepared by reduction of the corresponding 3-benzoyl compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.