Imidazoline derivatives

US3965112A · kind A · utility

Assignee

• John Wyeth & Brother Limited · GB

Inventors

• Alan C. White · Windsor, CA
• Robin Michael Black

Key dates

• Filing date: May 29, 1975
• Grant date: Jun 22, 1976
• Expiry date: May 29, 1995

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D243/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The disclosure relates to derivatives of imidazoline of the general formula ##SPC1## Or pharmaceutically acceptable acid addition salts thereof wherein R.sup.3 and R.sup.4 which may be the same or different each represent hydrogen or lower alkyl, Ph represents phenyl, halophenyl, lower alkyl phenyl, di(lower alkyl) phenyl or lower alkoxy phenyl, R is hydroxyl, lower alkoxy or halogen, R.sup.1 is phenyl, halophenyl, lower alkyl phenyl, di(lower alkyl)phenyl, lower alkoxy phenyl or napthyl and R.sup.6 is hydrogen or lower alkyl. The compounds have hypoglycemic activity.