4'-Fluoro-4-{[4-(phenyl)-4-alkoxy-cyclo-hexyl]amino}butyrophenones and the salts thereof
US3965180A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Feb 20, 1973 |
| Grant date | Jun 22, 1976 |
| Priority date | — |
| Expiry date | Feb 20, 1993 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C35/21
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to novel 4-(substituted alkoxy)-4-(substituted phenyl)cyclohexylamines embraced by the formula ##SPC1## Wherein .about. is a generic expression denoting cis and trans stereoconfiguration and mixtures thereof, with the proviso that when the stereoconfiguration of the linkage connecting the cyclohexane ring and R.sup.3 O is is cis to the amino group, the linkage connecting the cyclohexane and phenyl rings is always trans, and vice versa; R is selected from the group consisting of lower alkyl of 1 through 4 carbon atoms, chlorine, fluorine, bromine, trifluoromethyl, and lower alkoxy of 1 through 4 carbon atoms; R' has the same meaning as R and in addition hydrogen; R.sup.1 is selected from the group consisting of hydrogen and lower alkyl of 1 through 4 carbon atoms; R.sup.2 is selected from the group consisting of hydrogen, lower alkyl of 1 through 4 carbon atoms, ring monosubstituted aroylalkyl wherein the substituents have the same meaning as R and R', above, aryl is from 6 through 10 carbon atoms and alkyl of from 1 through 4 carbon atoms and bis (ring monosubstituted)arylalkyl wherein the substituents have the same meaning as R and R', above, aryl is from 6 …
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