2-Fluoromethyl-3-o-tolyl-6-amino-4(3H)-quinazolinone
US3966731A · kind A · utility
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Key dates
| Filing date | Sep 30, 1974 |
| Grant date | Jun 29, 1976 |
| Priority date | — |
| Expiry date | Sep 30, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/91
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
N-(2-amino-5-nitrobenzoyl)-o-toluidine is condensed with fluoroacetic acid or a functional derivative thereof. N-(2-fluoroacetamido-5-nitrobenzoyl)-o-toluidine obtained by said condensation reaction is dehydrated to produce 2-fluoromethyl-3-(o-tolyl)-6-nitro-4(3H)-quniazolinone, which is then subjected to reduction reaction. 2-fluoromethyl-3-(o-tolyl)-6-amino-4(3H)-quinazolinone thus obtained and a pharmaceutically acceptable acid addition salt thereof are useful as central muscle relaxants, minor tranquilizers, anti-convulsants, analgesics and/or anti-inflammatory agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.