Patent · US Expired

Ortho fused cycloalkano-4-quinolone-3-carboxylic acid derivatives

US3966743A · kind A · utility

39Cited by
5References
36Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 9, 1974
Grant dateJun 29, 1976
Priority date
Expiry dateSep 9, 1994

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D221/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Cycloalkano-quinolone derivatives having anti-microbial activity characterized by the formula: ##SPC1## Wherein one of R.sub.1 and R.sub.2 designates hydrogen, halogen, nitro, amino, hydroxyl, acylamino, acyloxy, alkoxy or aryloxy and the other taken together with R.sub.3 forms an akylene bridge containing 2 to 6 carbon atoms, X is hydrogen, lower alkyl, which may be substituted by a member of the group consisting of halogen, hydroxyl, acyloxy, alkoxy, aryloxy, aralkyloxy, mercapto, alkylmercapto, arylmercapto, arylsulfonyl, and alkylsulfonyl, or X is unsubstituted alkenyl including alkadienyl, or alkynyl and Y is hydroxyl, amino or lower alkoxy, and the pharmaceutically acceptable salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.