1-Phenyl-2-(Naphthylalkyl-amino)-ethanols and salts thereof

US3966814A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Kurt Schromm · Ingelheim am Rhein, DE
• Anton Mentrup · Mainz, DE
• Ernst-Otto Renth · Ingelheim am Rhein, DE
• Werner Traunecker · Münster-Sarmsheim, DE

Key dates

• Filing date: Jun 27, 1973
• Grant date: Jun 29, 1976
• Expiry date: Jun 27, 1993

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##SPC1## Wherein PA1 A is alkylene of 2 to 6 carbon atoms, PA1 R.sub.1 is hydrogen, lower alkyl, lower alkoxy, hydroxyl, or lower alkanoyloxy, PA1 R.sub.2 is hydrogen, lower alkyl or lower alkoxy, PA1 R.sub.3 is hydrogen, methyl or ethyl, PA1 R.sub.4 is hydrogen, lower alkyl or lower alkoxy, PA1 R.sub.5 is hydrogen, hydroxyl, lower alkanoyloxy or lower alkyl-sulfonamido, and PA1 R.sub.6 is hydrogen or lower alkanoyl, And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as peripheral vasodilators, antihistaminics and spasmolytics.