N,N'-disubstituted thioureas, their process of production and use as antimicrobial agents

US3966968A · kind A · utility

Assignee

• Henkel u. Cie GmbH

Inventors

• Hans Andree · Leichlingen, DE
• Gunther Koppensteiner
• Heinz-Ulrich Stracke

Key dates

• Filing date: Dec 18, 1973
• Grant date: Jun 29, 1976
• Expiry date: Dec 18, 1993

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C335/42
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to N,N'-disubstituted thioureas of the formula ##SPC1## Where X represents CO, SO.sub.2 or CH.sub.2, R' represents lower alkyl, a heterocycle or a possibly substituted phenyl, and R.sub.1, R.sub.2, and R.sub.3 represent hydrogen, lower alkyl, chlorine, bromine, nitro and carboxyl; as well as their methods of production and their use as antimicrobial substances, particularly against gram positive bacteria.