Process for the production of carnitine
US3969406A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Apr 28, 1975 |
| Grant date | Jul 13, 1976 |
| Priority date | — |
| Expiry date | Apr 28, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C229/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The process for the production of carnitine hydrochloride which includes reacting a .alpha.-haloacetoacetanilide having the formula: EQU XCH.sub.2 COCH.sub.2 CONYC.sub.6 H.sub.5 where X is a halogen atom and Y is a hydrogen atom, a phenyl group, a benzyl group or an alkyl group having 1 to 8 carbon atoms, with trimethylamine, a .gamma.-trimethylammonium acetoacetanilide halide resulting. The .gamma.-trimethylammonium acetoacetanilide halide, is hydrogenated, a .gamma.-trimethylammonium-.beta.-hydroxybutyric acid halide resulting. The .gamma.-trimethylammonium-.beta.-hydroxybutyric acid halide is converted by means of aqueous hydrochloric acid into the carnitine hydrochloride.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.