Novel substituted polyamides and process for producing them

US3970597A · kind A · utility

Inventors

• Mordechai Sokolovsky · Nes Ziona, IL
• Amihay Freeman · Rishon LeZion, IL
• Leon Goldstein · Chaville, FR

Key dates

• Filing date: Jun 4, 1974
• Grant date: Jul 20, 1976
• Expiry date: Jun 4, 1994

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08G69/48
• WIPO field: Macromolecular chemistry, polymers
• WIPO sector: Chemistry

Abstract

Novel substituted polyamides of the general formula ##EQU1## wherein A and B, which may be identical or different, are the hydrocarbon backbone groups of the formula --(CH.sub.2).sub.n --, where n is an integer, R.sub.2 and R.sub.3 are the residues of an aldehyde R.sub.2 --CHO or of an isocyanide R.sub.3 --N.tbd.C, where R.sub.2 and R.sub.3 are aliphatic, aromatic or heterocyclic residues of the respective aldehyde or isocyanide, or where R.sub.3 is a chromophoric moiety. R.sub.2 and R.sub.3 can be substituted, and amongst the possible substituents there may be R.sub.3 designating --(CH.sub.2).sub.n --NHCO--CHR.sub.2 --N(CO)(R.sub.4)--X, where R.sub.4 is the residue of a monocarboxylic or dicarboxylic acid and X is the lysyl residue of a protein, which may be biologically active, or the residue of a low-molecular weight compound containing a primary amine moiety. Preferred polyamides are various types of nylons. Amongst proteins chemically bound to the polyamide there may be mentioned enzymes, antibodies and peptide hormones. When R.sub.3 is a chromophoric moiety, the product is a chemically dyed polyamide. The invention relates also to a process for the production of such novel su…