11,15-Dihydroxy-9-oxoprost-13-ynoic acid
US3970683A · kind A · utility
1Cited by
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9Claims
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Key dates
| Filing date | Nov 12, 1974 |
| Grant date | Jul 20, 1976 |
| Priority date | — |
| Expiry date | Nov 12, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/062
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
3-(Optionally oxygenated)-5-oxocyclopent-1-enealkanoic acids and their alkyl esters are allowed to react with appropriate alkenyl copper, alkenyl boron, alkynyl boron, alkynyl gallium or alkynyl aluminum compounds to produce the corresponding 2-(3-hydroxy-3-[optionally alkylated]-1-alkenyl)cyclopentanealkanoic acids, 2-(3-hydroxy-3-[optionally alkylated]-1-alkynyl)cyclopentanealkanoic acids and their esters. The prostaglandin derivatives so produced are valuable and useful as pharmacological agents as is evidenced by their central nervous system-affective, anti-bacterial, anti-fungal and prostaglandin antagonist activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.