Cycloalkyl phenoxy carboxylic acid derivatives
US3970694A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 28, 1974 |
| Grant date | Jul 20, 1976 |
| Priority date | — |
| Expiry date | Jun 28, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C69/712
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel compounds having the formula, ##SPC1## Wherein R.sub.1, R.sub.2 and R.sub.3 are each independently hydrogen or a C.sub.1 -C.sub.4 alkyl; n is an integer of 4-6; and Y is hydrogen or a group of the formula ##EQU1## wherein R.sub.1, R.sub.2 and R.sub.3 are as defined above. These compounds are produced, for example, by reacting a bisphenolic compound of the formula, ##SPC2## With chloroform and a ketone compound of the formula, EQU R.sub.1 -- CO -- R.sub.2 in the presence of an alkali. Alternatively, they are produced by reacting the bisphenolic compound with .alpha.-halogeno- or .alpha.-hydroxycarboxylic acid derivative of the formula, ##EQU2## wherein R.sub.1, R.sub.2, and R.sub.3 are as defined above, and X is a halogen or hydroxyl. The novel compounds are anti-atherosclerosis agents useful for lowering elevated levels of cholesterol or lipids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.