Esters of carboxylic acids formally substituted by sodium or potassium in the alpha-position and the method for their preparation
US3971816A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 21, 1974 |
| Grant date | Jul 27, 1976 |
| Priority date | — |
| Expiry date | Nov 21, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F1/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to new esters of carboxylic acids formally substituted in the alpha-position by sodium or potassium which have the formula EQU R.sup.1 R.sup.2 CMCOOR.sup.3 (1) where PA1 R.sup.1 is H, C.sub.1 to C.sub.16 linear or branched alkyl, phenyl or tolyl PA1 R.sup.2 is C.sub.1 to C.sub.6 linear or branched alkyl, PA1 R.sup.3 is C.sub.1 to C.sub.12 linear or branched alkyl, and M is Na or K and to a method for their preparation consisting in the reaction of a carboxylic acid ester with An or K salt of hexamethyldisilazane. The reaction is carried out in a hydrocarbon medium which may contain up to 20 vol.-% of organic ether and at -80.degree. to +50.degree. C, while the molar ratio of amide salt to ester is 0.7 to 1.5. The preparation can be also carried out in the presence of alkali metal alkoxide C.sub.3 to C.sub.16 with the straight or branched molecule at the alkoxide - to - metallo ester ratios 0.5 to 20, giving the addition product of alpha-metallo ester and alkoxide. The invention further relates to the preparation of the aforesaid alpha-metallo esters by the exchange reaction between the ester of alpha.lithio carboxylic acid and Na or K alkoxide carried out at -…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.