Patent · US Expired

Pharmaceutical compositions containing 1,4-bis-(5'-nitroimidazolyl-2'-methylene-imino) piperazine compounds for treating protozoal diseases and methods for treating such diseases

US3973019A · kind A · utility

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1References
10Claims
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Assignee

Inventors

Key dates

Filing dateDec 20, 1974
Grant dateAug 3, 1976
Priority date
Expiry dateDec 20, 1994

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

1,4-BIS-5'-NITROIMIDAZOLYL-2'-METHYLENE-IMINO) PIPERAZINES OF THE FORMULA ##SPC1## In which R.sub.1 is hydrogen, methyl, ethyl or 2-hydroxyethyl and R.sub.2 is hydrogen or methyl, are prepared by reaction of 5-nitro-imidazolyl-2-aldehydes or the functional derivatives thereof with 1,4-diamino-piperazines. Pharmaceutical compositions containing these compounds for treating protozoal diseases and methods of treating protozoal diseases with these compounds are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.