Patent · US Expired

Solid phase radioimmunoassay

US3975511A · kind A · utility

10Cited by
3References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 1, 1974
Grant dateAug 17, 1976
Priority date—
Expiry dateMar 1, 1994

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/815
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Method of determining the concentration of a substance in a solution which comprises the steps of incubating the solution with a known amount of radioactively labelled substance and a suspendable composite consisting of anti-substance antibody coupled chemically through an intermediate silane coupling agent to an inorganic carrier, the incubation period being for a time sufficient to form immunochemical complexes, separating the complexes from the solution, determining the radioactivity of either the separated complexes or the remaining solution, and relating that determination to a standard curve. Specific assays for digoxin, insulin, and estriol are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.