Production of pyridyl ketones
US3979400A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 11, 1974 |
| Grant date | Sep 7, 1976 |
| Priority date | — |
| Expiry date | Dec 11, 1994 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/582
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Pyridyl ketones are produced from substituted pyridines containing at least one lower alkyl group or aryl-methylene group connected to a carbon of the pyridine nucleus by a methylene radical of such group, by air oxidizing the pyridine in the liquid phase at elevated temperature, e.g., 200.degree. C., and pressure, e.g., 400 psig. The reaction is preferably carried out in the presence of an inorganic oxidation catalyst, such as a heavy metal or oxide or hydrated oxide or inorganic salt thereof, but with some pyridines, especially 2-substituted and 4-substituted pyridines, reaction occurs without a catalyst. The reaction mixture is fractionated to recover the pyridyl ketone and unreacted starting material.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.