Preparation of rapidly resorbable glibenclamide

US3979520A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Werner Rothe · Rellingen, DE
• Helmut Heinemann · Kelkheim, DE
• Felix Helmut Schmidt
• Gunter Betzien

Key dates

• Filing date: Sep 20, 1974
• Grant date: Sep 7, 1976
• Expiry date: Sep 20, 1994

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/64
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Rapidly resorbable particulate glibenclamide having a particle surface area of active material of at least 3 m.sup.2 /g is produced by precipitating the active material from its solution in an organic solvent or in water or aqueous alcohol, preferably rendered alkaline, using water which is preferably acidified.