Preparation of a diagnostic agent for measuring the coagulability of blood
US3983004A · kind A · utility
18Cited by
4References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 11, 1974 |
| Grant date | Sep 28, 1976 |
| Priority date | — |
| Expiry date | Nov 11, 1994 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A diagnostic agent containing thromboplastin sensitive to factor VII and factor X for measuring the coagulability of blood is prepared by extracting an aqueous suspension of thrombogenic tissue at pH 10 to 12, acidifying the extract, separating the extract from the tissue and adding a water-soluble calcium salt to the extract. The agent can be stabilized by adding to the extract cholanic acid and a water-soluble heavy metal-II-salt.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.