Amidoxime derivatives and process for preparing the same
US3984470A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 28, 1975 |
| Grant date | Oct 5, 1976 |
| Priority date | — |
| Expiry date | Jul 28, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/86
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Amidoxime derivatives corresponding to the general formula: ##EQU1## and pharmaceutically acceptable acid addition salts thereof, wherein R.sub.1 and R.sub.2, which are the same or different, represent hydrogen or a straight-chain lower alkyl radical containing from 1 to 3 carbon atoms, n is 0, 1 or 2 and R is selected from the groups consisting of: ##SPC1## Wherein X represents oxygen or sulphur, Y . . . Z represents HC--CH or C=C, R.sub.3 and R.sub.4, which are the same or different, represent hydrogen or a branched- or straight-chain lower alkyl radical containing from 1 to 3 carbon atoms with the provisos that: PA1 A. when n is 1, R.sub.1 and R.sub.2 are each hydrogen and R is selected from the groups A, B, C and D. PA1 b. when n is 2, R.sub.1 and R.sub.2 area each hydrogen and R is selected from the groups A, B, C and the group D when it represents .beta.-naphthyl. They are effective as antidepressive and antiaggressive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.