Purification of .gamma.-oxo-2-dibenzofuranbutyric acid
US3985774A · kind A · utility
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6References
2Claims
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Key dates
| Filing date | Oct 30, 1972 |
| Grant date | Oct 12, 1976 |
| Priority date | — |
| Expiry date | Oct 30, 1992 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/91
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the separation of .gamma.-oxo-2-dibenzofuranbutyric acid from a mixture of said acid and .gamma.-oxo-3-dibenzofuranbutyric acid is disclosed. Such a mixture is obtained by the prior art method of preparing .gamma.-oxo-2-dibenzofuranbutyric acid from dibenzofuran and succinic anhydride in a Friedel-Crafts reaction. The mixture of acids is converted to a mixture of their corresponding lower alkyl esters which is separated by recrystallization or chromatography into its component alkyl esters. Hydrolysis of the lower alkyl ester of .gamma.-oxo-2-dibenzofuranbutyric acid gives the desired corresponding acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.