Tetrahydro-azepinoquinolines

US3987047A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Gerhart Griss · Zell am Harmersbach, DE
• Rudolf Hurnaus · Großenhain, DE
• Wolfgang Grell · Biberach, DE
• Robert Sauter · Biberach, DE
• Richard Reichl · Ingelheim am Rhein, DE

Key dates

• Filing date: Nov 5, 1974
• Grant date: Oct 19, 1976
• Expiry date: Nov 5, 1994

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##SPC1## Wherein ##EQU1## where R.sub.1 is hydrogen, straight or branched aliphatic acyl of 1 to 12 carbon atoms, methoxy-substituted straight or branched aliphatic acyl of 1 to 12 carbon atoms, benzoyl, halo-benzoyl, carbalkoxy of 2 to 7 carbon atoms, carbcycloalkoxy of 4 to 7 carbon atoms, benzyl, methylbenzyl, phenylsulfonyl, halo-phenylsulfonyl, tolylsulfonyl, alkenyl of 2 to 6 carbon atoms, phenyl, trifluoroacetyl, amidino, amido, thioamido, phenoxycarbonyl, benzyloxycarbonyl, methylsulfonyl or EQU --B -- X where PA2 B is straight or branched alkylene of 1 to 6 carbon atoms, and PA2 X is hydrogen, hydroxyl, methoxy, carboxyl, cyano, dimethylaminocarbonyl, morpholino-carbonyl or carbalkoxy of 2 to 6 carbon atoms, PA1 R.sub.2 is hydrogen, hydroxyl, alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 3 carbon atoms, alkanoyloxy of 1 to 3 carbon atoms, alkoxycarbonyloxy of 2 to 4 carbon atoms, amino, dimethylamino, morpholino or halogen, PA1 R.sub.3 is hydrogen, halogen, hydroxyl, carboxyl, straight or branched alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 6 carbon atoms, alkoxy of 1 to 3 carbon atoms, phenyl-alkoxy of 1 to 3 carbon atoms, carbalkoxy of 2 to 4…