Derivatives of phenoxy isobutyric acid having hypolipemizing and hypocholesterolemizing action
US3987175A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | May 14, 1975 |
| Grant date | Oct 19, 1976 |
| Priority date | — |
| Expiry date | May 14, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/89
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to new chemical products which are useful as hypolipemizing and hypocholesterolemizing agents. The new compounds are derivatives of phenoxy isobutyric acid of the general formula ##EQU1## wherein: A is a lower-alkylene bridge of 2 to 6 carbon atoms, either linear or branched, X is a halogen atom, R = h or lower-alkyl, The N of the pyridyl ring can be replaced by an N-oxide, or the compounds can be in the form of their pharmaceutically-acceptable acid addition salts. Pharmaceutical compositions containing these active principles are useful for hypolipemizing and hypocholesterolemizing purposes, e.g., in the prevention and treatment of atherosclerosis and its consequences.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.