Anti-inflammatory composition and method containing cyclic 2-furfural-acetals

US3987189A · kind A · utility

Assignee

• Henkel u. Cie GmbH

Inventors

• Hans Andree · Leichlingen, DE
• Christian Gloxhuber · Bernau, DE
• Hinrich Moller · Monheim, DE
• Ferdi Saygin

Key dates

• Filing date: Jun 11, 1974
• Grant date: Oct 19, 1976
• Expiry date: Jun 11, 1994

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S424/05
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Anti-inflammatory cyclic 2-furfural-acetals of the formula ##SPC1## In which X is hydrogen, a lower alkyl preferably having 1 to 4 carbon atoms, or nitro, Z is an alkylene of the formula EQU --CR.sub.1 R.sub.2 --CR.sub.3 R.sub.4 --(CR.sub.5 R.sub.6).sub.m --(CR.sub.7 R.sub.8).sub.n --(CR.sub.9 R.sub.10).sub.p --, in which R.sub.1 to R.sub.6 are, independently of one another, hydrogen, alkyl having 1 to 26 carbon atoms, hydroxyalkyl, or aryl, R.sub.7 to R.sub.10 are independently of one another, hydrogen or lower alkyl preferably having 1 to 4 carbon atoms, R.sub.1 and R.sub.3 or R.sub.1 and R.sub.5 may, together with their associated carbon atom, represent a carbocyclic ring system with 5 to 8 carbon atoms, and m, n and p are 0 or 1, as used in cosmetic preparations for the prevention and control of inflammation, and methods for the prevention and control of inflammation.