Process for production of spherical porous fillers for liquid chromatography by suspension polymerization of monovinyl and polyvinyl aromatic monomers in the presence of paraffin wax
US3989649A · kind A · utility
37Cited by
2References
15Claims
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Key dates
| Filing date | Jun 3, 1975 |
| Grant date | Nov 2, 1976 |
| Priority date | — |
| Expiry date | Jun 3, 1995 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2220/54
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Spherical porous fine particles of a cross-linked polymer can be obtained in the continuous phase by subjecting a mixture of a monovinyl aromatic compound and a polyvinyl aromatic compound to aqueous suspension polymerization in the presence of a paraffin wax with use of an initiator. This product is very suitable as a filler for gel permeation chromatography. Ion exchange groups can be introduced into the obtained polymer and a column filler suitable for ion exchange chromatography of amino acids, substances related to nucleic acids, proteins and the like is thus obtained.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.