Method of racemizing optically active N-acylamino acids
US3991077A · kind A · utility
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1References
9Claims
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Key dates
| Filing date | Mar 3, 1975 |
| Grant date | Nov 9, 1976 |
| Priority date | — |
| Expiry date | Mar 3, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Optically active amino acids N-acylated with carboxylic acids are readily racemized without decomposition at elevated temperature in inert organic solvents in which they are homogeneously soluble at the racemization temperature. When the deacylated amino acid is insoluble or only sparingly soluble in the solvent, the method permits a convenient work-up of the products of enzymatic deacylation of one enantiomorph of the N-acylamino acid in which the remaining enantiomorph is racemized for recycling to the deacylation step.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.