Compositions and method of treating with component B of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steriods
US3992534A · kind A · utility
12Cited by
3References
47Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 6, 1975 |
| Grant date | Nov 16, 1976 |
| Priority date | — |
| Expiry date | Nov 6, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J71/0031
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the resolution of stereoisomeric mixtures of certain steroids obtained by synthesis into its components, comprising subjecting the stereoisomeric mixture to gel filtration, the components in view of different retention volumes being separated and being separately recoverable; and stereoisomeric components A and B thereby obtained, pharmaceutical compositions thereof; and method of treating inflammation therewith. This application claims pharmaceutical compositions and method of employing Component B of the novel steroid stereoisomeric mixtures, including both the free 21-hydroxyl and the 21-acetates thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.