Patent · US Expired

2-[(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8- yl)alkyl]-1H-benz[de]isoquinolin-1,3(2H)-diones

US3996363A · kind A · utility

13Cited by
18References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 13, 1975
Grant dateDec 7, 1976
Priority date
Expiry dateJun 13, 1995

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of the following formula and their acid addition salts ##STR1## wherein R.sup.1 and R.sup.2 are selected from hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen, trifluoromethyl, amino, nitro and cyano; R.sup.3 is hydrogen, lower alkyl or lower alkenyl; R.sup.4 is hydrogen, halogen, or lower alkyl; and A is straight or branched chain alkylene are disclosed. These compounds exhibit antidepressant activity. In addition, these compounds are useful as antiinflammatory agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.