Process of preparing 2-amino-4-hydroxy-5(and/or 6)-alkyl substituted pyrimidines
US3997537A · kind A · utility
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Key dates
| Filing date | May 12, 1975 |
| Grant date | Dec 14, 1976 |
| Priority date | — |
| Expiry date | May 12, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D315/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for the preparation of a compound of formula: ##STR1## WHEREIN N IS ZERO OR AN INTEGER FROM 1 TO 12 AND R.sup.1 and R.sup.2 are hydrogen or lower alkyl, which comprises the step of treating a mixture of a diketene of formula: ##STR2## and a strongly acidic medium selected from the group consisting of concentrated sulphuric acid and oleum with a compound of formula: PAC NH=C(NH.sub.2)NR.sup.1 R.sup.2 or the sulphate thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.