Pharmaceutical compositions containing an amphetamine derivative for the alleviation of anxiety or treatment of depression
US4000280A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 30, 1975 |
| Grant date | Dec 28, 1976 |
| Priority date | — |
| Expiry date | Jun 30, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds having the general formula ##STR1## or pharmaceutically acceptable salts thereof, in which formula R.sup.1 and R.sup.2 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R.sup.3 represents a lower alkyl group or a benzyl group, R.sup.4 represents a hydrogen atom, a lower alkyl group, a benzyl group or a CH.sub.2 CH.sub.2 CH.sub.2 -bridge connected to the phenyl ring in ortho-position relative to the N-substituent, R.sup.5 represents a hydrogen atom or a methyl group and R.sup.6 represents a lower alkyl group, provided that R.sup.1 and/or R.sup.2 represents a lower alkyl group or a halogen atom where R.sup.3 represents a methyl group, R.sup.4 represents a methyl group and R.sup.5 represents a hydrogen atom; methods for the preparation thereof; intermediates useful for their preparation; pharmaceutical preparations containing at least one of these compounds; and the use thereof in the treatment of depressive states and alleviating anxiety.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.