Pyrazole derivatives
US4000281A · kind A · utility
17Cited by
0References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 6, 1971 |
| Grant date | Dec 28, 1976 |
| Priority date | — |
| Expiry date | Dec 6, 1991 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Pyrazole derivatives of the general formula: ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen, methyl, ethyl, n-propyl, isopropyl, or n-butyl and X is hydrogen, hydroxy, methyl, methoxy, chlorine, or bromine, and their acid addition salts have antiviral activity against both RNA and DNA viruses such as myxoviruses, adenoviruses, rhinoviruses, and various viruses of the Herpes group. The compounds are active when administered orally or topically. They may be prepared by heating hydrazine hydrate or an alkyl hydrazine with a 3-benzofuryl ketone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.