Measuring system for the pharmacological manipulation of the coagulation mechanism in blood and for the elapsed coagulation time
US4000972A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 16, 1976 |
| Grant date | Jan 4, 1977 |
| Priority date | — |
| Expiry date | Jan 16, 1996 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/142222
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system for determining the coagulation time of blood and components thereof, the amount of anticoagulant to be injected before and during surgery, and the amount of additive required to neutralize the anticoagulated blood during and after surgery. With collected samples of anticoagulated blood inserted into the system coagulation of the blood is accelerated through the controlled injection of a neutralizing additive by a corresponding injection of regulated gas. Failsafe means determine if gas is being injected into the sample and detection means detect the event of coagulation and indicate the elapsed time for coagulation. Before surgery, an anticoagulant is added to the patient's blood in a quantity necessary to avoid coagulation during surgery. The system responsive to the parameters of the patient's sex, height, and weight and/or pump volume and blood volume determines the amount of anticoagulant to be injected. During operation, samples of blood are periodically taken and analyzed to determine additional amounts of anticoagulant or neutralizing additive to inject. To neutralize the anticoagulant by the injection of a suitable additive immediately after surgery, the system de…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.