Stabilized choline salicylate compounds
US4001311A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 24, 1975 |
| Grant date | Jan 4, 1977 |
| Priority date | — |
| Expiry date | Oct 24, 1995 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Choline salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds of the formula, ##STR1## wherein Me represents the sodium, potassium or lithium ion and R represents the sulfite, bisulfite metabisulfite, dithionate, hydrosulfite and hyposulfite groups are described. Said compounds are stable and inhibit the formation of color in pharmaceutical preparations containing the same. The method for the preparation of choline salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds, and pharmaceutical dosage forms containing the same are disclosed together with a method for their use to inhibit color formation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.