Compounds with ergoline skeleton
US4005089A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 22, 1975 |
| Grant date | Jan 25, 1977 |
| Priority date | — |
| Expiry date | May 22, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D457/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New compounds of the general formula (I) ##STR1## wherein R stands for hydrogen or methyl group, x y stands for a group of the formula ##STR2## and R.sub.1 stands for a group of the formula (III), (IV) or (V) ##STR3## wherein n is an integer from 4 to 10, ARE PREPARED BY ACYLATING A COMPOUND OF THE GENERAL FORMULA (II), ##STR4## wherein R and x y each have the same meanings as defined above, and R.sub.2 stands for a group of the formula (VI), (VII) or (VIII), ##STR5## with a C.sub.6-12 carboxylic acid or a C.sub.6-12 carboxylic acid halide. The new compounds of the general formula (I) and their acid addition salts can be used as antidepressants and antiserotonine agents with prolonged effects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.