1-[(Dimethylamino)-methyl]-6-aryl-4H-imidazo[1,5-a][1,4]benzodiazepines
US4005099A · kind A · utility
12Cited by
1References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 21, 1975 |
| Grant date | Jan 25, 1977 |
| Priority date | — |
| Expiry date | Nov 21, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula III ##STR1## wherein R.sub.1 is hydrogen or methyl; wherein R.sub.2 is hydrogen, fluoro, chloro, bromo, trifluoromethyl, or nitro; and wherein Ar is phenyl, o-chlorophenyl, o-fluorophenyl, o,o-difluorophenyl, or 2-pyridyl, are produced by a two-step process. The compounds of formula III as well as their pharmacologically acceptable acid addition salts thereof are antidepressant agents possessing additionally antianxiety activity. Thus these compounds III are useful in the treatment of anxieties in mammals and birds, and also as anti-depressants in man.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.